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Published in Nature Communications, 2018
This paper conducted the largest T2D meta-analysis of GWAS and identified 139 common and 4 rare variants associated with T2D.
Recommended citation: Angli Xue*, Yang Wu*, Zhihong Zhu, Futao Zhang, Kathryn E Kemper, Zhili Zheng, …, Jian Zeng#, Jian Yang#. Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Nature Communications. 12, 6450 (2018). https://www.nature.com/articles/s41467-018-04951-w
Published in Nature Communications, 2021
This paper demonstrated that behavioural traits are subject to misreports and longitudinal changes (MLC) which can cause biases in GWAS and follow-up analyses.
Recommended citation: Angli Xue, Longda Jiang, Zhihong Zhu, Naomi R. Wray, Peter M. Visscher, Jian Zeng, Jian Yang. Genome-wide analyses of behavioral traits are subject to bias by misreports and longitudinal changes. Nature Communications. 12, 6450 (2021). https://www.nature.com/articles/s41467-020-20237-6
Published in Genome Biology, 2023
This paper discussed the pitfalls and opportunities when using latent variables in the single-cell eQTL mapping analysis.
Recommended citation: Angli Xue#, Seyhan Yazar, Drew Neavin, Joseph E. Powell#. "Pitfalls and opportunities for applying latent variables in single-cell eQTL analyses". Genome Biology. 24.1 (2023): 1-11. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-023-02873-5